4uuj
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4uuj]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UUJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UUJ FirstGlance]. <br> | <table><tr><td colspan='2'>[[4uuj]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UUJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UUJ FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=DGA:DIACYL+GLYCEROL'>DGA</scene>, <scene name='pdbligand=F09:NONAN-1-OL'>F09</scene>, <scene name='pdbligand=IND:INDOLE'>IND</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=XA7:TETRAHEXYL+AMMONNIUM'>XA7</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=DGA:DIACYL+GLYCEROL'>DGA</scene>, <scene name='pdbligand=F09:NONAN-1-OL'>F09</scene>, <scene name='pdbligand=IND:INDOLE'>IND</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=XA7:TETRAHEXYL+AMMONNIUM'>XA7</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uuj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uuj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uuj RCSB], [http://www.ebi.ac.uk/pdbsum/4uuj PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uuj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uuj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uuj RCSB], [http://www.ebi.ac.uk/pdbsum/4uuj PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/KCSA_STRLI KCSA_STRLI]] Acts as a pH-gated potassium ion channel; changing the cytosolic pH from 7 to 4 opens the channel, although it is not clear if this is the physiological stimulus for channel opening. Monovalent cation preference is K(+) > Rb(+) > NH4(+) >> Na(+) > Li(+).<ref>PMID:7489706</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Burdette, D | + | [[Category: Burdette, D]] |
| - | [[Category: Focia, P J | + | [[Category: Focia, P J]] |
| - | [[Category: Gross, A | + | [[Category: Gross, A]] |
| - | [[Category: Lenaeus, M J | + | [[Category: Lenaeus, M J]] |
| - | [[Category: Wagner, T | + | [[Category: Wagner, T]] |
[[Category: Immune system-metal transport complex]] | [[Category: Immune system-metal transport complex]] | ||
[[Category: Ion transport]] | [[Category: Ion transport]] | ||
Revision as of 05:20, 25 December 2014
POTASSIUM CHANNEL KCSA-FAB WITH TETRAHEXYLAMMONIUM
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