3n7k
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n7k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3n7k RCSB], [http://www.ebi.ac.uk/pdbsum/3n7k PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n7k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3n7k RCSB], [http://www.ebi.ac.uk/pdbsum/3n7k PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BXC1_CLOBO BXC1_CLOBO]] Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that cleaves syntaxin. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 05:24, 25 December 2014
Crystal structure of botulinum neurotoxin serotype C1 binding domain
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