1sis
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sis OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1sis RCSB], [http://www.ebi.ac.uk/pdbsum/1sis PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sis OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1sis RCSB], [http://www.ebi.ac.uk/pdbsum/1sis PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SCX5_BUTEU SCX5_BUTEU]] Toxin with unknown function in healthy organisms. On glioma cells, interacts with chloride channels (probably Clc-3/CLCN3) and MMP2 at the surface of glioma cells. This complex is then internalized via caveolae, thus inhibiting the chloride channels necessary for cell shrinkage and tumor propagation (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 05:31, 25 December 2014
SPATIAL STRUCTURE OF INSECTOTOXIN I5A BUTHUS EUPEUS BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY (RUSSIAN)
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