3qrb
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qrb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qrb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qrb RCSB], [http://www.ebi.ac.uk/pdbsum/3qrb PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qrb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qrb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qrb RCSB], [http://www.ebi.ac.uk/pdbsum/3qrb PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CADH1_MOUSE CADH1_MOUSE]] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7 (By similarity). E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production (By similarity). | ||
==See Also== | ==See Also== | ||
Revision as of 05:33, 25 December 2014
crystal structure of E-cadherin EC1-2 P5A P6A
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