3vqg

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vqg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vqg RCSB], [http://www.ebi.ac.uk/pdbsum/3vqg PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vqg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vqg RCSB], [http://www.ebi.ac.uk/pdbsum/3vqg PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/IGSF5_MOUSE IGSF5_MOUSE]] Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells.<ref>PMID:12773569</ref> <ref>PMID:16982697</ref>
==See Also==
==See Also==
*[[Ubiquitin protein ligase|Ubiquitin protein ligase]]
*[[Ubiquitin protein ligase|Ubiquitin protein ligase]]
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== References ==
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<references/>
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</StructureSection>
</StructureSection>

Revision as of 05:33, 25 December 2014

Crystal Structure Analysis of the PDZ Domain Derived from the Tight Junction Regulating Protein

3vqg, resolution 1.35Å

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