1jo8
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1jo8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JO8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JO8 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1jo8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JO8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JO8 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jo8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jo8 RCSB], [http://www.ebi.ac.uk/pdbsum/1jo8 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jo8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jo8 RCSB], [http://www.ebi.ac.uk/pdbsum/1jo8 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ABP1_YEAST ABP1_YEAST]] Regulates ARP2/3 complex-mediated actin assembly. Recruits ARP2/3 complex to sides of preexisting actin filaments, which may promote nucleation or stabilization of filament branches. Binds to actin filaments, but not actin monomers. Actin binding is required for ARP2/3 complex activation. May also have a role in linking the actin cytoskeleton to endocytosis. recruits components of the endocytotic machinery to cortical actin patches, known sites of endocytosis.<ref>PMID:11331312</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
| - | [[Category: Castagnoli, L | + | [[Category: Castagnoli, L]] |
| - | [[Category: Cesareni, G | + | [[Category: Cesareni, G]] |
| - | [[Category: Cope, M J | + | [[Category: Cope, M J]] |
| - | [[Category: Douangamath, A | + | [[Category: Douangamath, A]] |
| - | [[Category: Drubin, D G | + | [[Category: Drubin, D G]] |
| - | [[Category: Fazi, B | + | [[Category: Fazi, B]] |
| - | [[Category: Ferracuti, S | + | [[Category: Ferracuti, S]] |
| - | [[Category: Schirwitz, K | + | [[Category: Schirwitz, K]] |
| - | [[Category: Wilmanns, M | + | [[Category: Wilmanns, M]] |
| - | [[Category: Zucconi, A | + | [[Category: Zucconi, A]] |
[[Category: Sh3 domain actin-binding-protein]] | [[Category: Sh3 domain actin-binding-protein]] | ||
[[Category: Structural protein]] | [[Category: Structural protein]] | ||
Revision as of 05:37, 25 December 2014
Structural analysis of the yeast actin binding protein Abp1 SH3 domain
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