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1j3l

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1j3l]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J3L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J3L FirstGlance]. <br>
<table><tr><td colspan='2'>[[1j3l]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J3L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J3L FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j3l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j3l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1j3l RCSB], [http://www.ebi.ac.uk/pdbsum/1j3l PDBsum], [http://www.topsan.org/Proteins/RSGI/1j3l TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j3l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j3l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1j3l RCSB], [http://www.ebi.ac.uk/pdbsum/1j3l PDBsum], [http://www.topsan.org/Proteins/RSGI/1j3l TOPSAN]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/RRAA_THET8 RRAA_THET8]] Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
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[[Category: Miyano, M.]]
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[[Category: Miyano, M]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Rehse, P H.]]
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[[Category: Tahirov, T H.]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
[[Category: Structural genomic]]
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[[Category: Rehse, P H]]
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[[Category: Tahirov, T H]]
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[[Category: Rsgi]]
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Vitamine k2]]
[[Category: Vitamine k2]]

Revision as of 06:01, 25 December 2014

Structure of the RNA-processing inhibitor RraA from Thermus thermophilis

1j3l, resolution 2.30Å

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