4l59
From Proteopedia
(Difference between revisions)
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| - | + | ==Crystal structure of the 3-MBT repeat domain of L3MBTL3 and UNC2533 complex== | |
| - | + | <StructureSection load='4l59' size='340' side='right' caption='[[4l59]], [[Resolution|resolution]] 2.29Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | ==Function== | + | <table><tr><td colspan='2'>[[4l59]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L59 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4L59 FirstGlance]. <br> |
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1VZ:4-(PYRROLIDIN-1-YL)-1-{4-[2-(PYRROLIDIN-1-YL)ETHYL]PHENYL}PIPERIDINE'>1VZ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">L3MBTL3, KIAA1798, MBT1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l59 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l59 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l59 RCSB], [http://www.ebi.ac.uk/pdbsum/4l59 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
[[http://www.uniprot.org/uniprot/LMBL3_HUMAN LMBL3_HUMAN]] Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Required for normal maturation of myeloid progenitor cells (By similarity). | [[http://www.uniprot.org/uniprot/LMBL3_HUMAN LMBL3_HUMAN]] Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Required for normal maturation of myeloid progenitor cells (By similarity). | ||
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
[[Category: Human]] | [[Category: Human]] | ||
| - | [[Category: Arrowsmith, C H | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Baughman, B M | + | [[Category: Baughman, B M]] |
| - | [[Category: Bountra, C | + | [[Category: Bountra, C]] |
| - | [[Category: Brown, P J | + | [[Category: Brown, P J]] |
| - | [[Category: Camerino, M A | + | [[Category: Camerino, M A]] |
| - | [[Category: Dickson, B M | + | [[Category: Dickson, B M]] |
| - | [[Category: Dong, A | + | [[Category: Dong, A]] |
| - | [[Category: Edwards, A M | + | [[Category: Edwards, A M]] |
| - | [[Category: Frye, S V | + | [[Category: Frye, S V]] |
| - | [[Category: Graslund, S | + | [[Category: Graslund, S]] |
| - | [[Category: James, L I | + | [[Category: James, L I]] |
| - | [[Category: Janzen, W P | + | [[Category: Janzen, W P]] |
| - | [[Category: Kireev, D B | + | [[Category: Kireev, D B]] |
| - | [[Category: Norris, J L | + | [[Category: Norris, J L]] |
| - | [[Category: Ravichandran, M | + | [[Category: Ravichandran, M]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Zhong, N | + | [[Category: Zhong, N]] |
[[Category: 3-mbt repeat domain]] | [[Category: 3-mbt repeat domain]] | ||
[[Category: L3mbtl3]] | [[Category: L3mbtl3]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
| - | [[Category: Structural genomic]] | ||
| - | [[Category: Structural genomics consortium]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Unc2533]] | [[Category: Unc2533]] | ||
Revision as of 06:02, 25 December 2014
Crystal structure of the 3-MBT repeat domain of L3MBTL3 and UNC2533 complex
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Categories: Human | Arrowsmith, C H | Baughman, B M | Bountra, C | Brown, P J | Camerino, M A | Dickson, B M | Dong, A | Edwards, A M | Frye, S V | Graslund, S | James, L I | Janzen, W P | Kireev, D B | Norris, J L | Ravichandran, M | Structural genomic | Zhong, N | 3-mbt repeat domain | L3mbtl3 | Sgc | Transcription | Unc2533
