3nwt
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nwt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nwt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nwt RCSB], [http://www.ebi.ac.uk/pdbsum/3nwt PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nwt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nwt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nwt RCSB], [http://www.ebi.ac.uk/pdbsum/3nwt PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CDC13_YEAST CDC13_YEAST]] Single-stranded telomeric DNA-binding protein that regulates telomere replication. Has a role in both positive and negative regulation. Promotes [TG(1-3)] strand lengthening via interaction with EST1. Promotes [C(1-3)A] strand re-synthesis by DNA polymerase alpha via interaction with POL1. Negatively regulates telomere elongation of the G strand via binding with STN1 thereby inhibiting telomerase activity.<ref>PMID:11230149</ref> <ref>PMID:11390652</ref> <ref>PMID:10898792</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 06:12, 25 December 2014
Crystal structure of the N-terminal domain of the yeast telomere-binding and telomerase regulatory protein Cdc13
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