1t90

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1t90]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T90 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1T90 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1t90]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T90 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1T90 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MMSA, IOLA, E83A, BSU39760 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MMSA, IOLA, E83A, BSU39760 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methylmalonate-semialdehyde_dehydrogenase_(acylating) Methylmalonate-semialdehyde dehydrogenase (acylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.27 1.2.1.27] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methylmalonate-semialdehyde_dehydrogenase_(acylating) Methylmalonate-semialdehyde dehydrogenase (acylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.27 1.2.1.27] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1t90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t90 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1t90 RCSB], [http://www.ebi.ac.uk/pdbsum/1t90 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1t90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t90 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1t90 RCSB], [http://www.ebi.ac.uk/pdbsum/1t90 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MMSA_BACSU MMSA_BACSU]] Converts malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively.<ref>PMID:16332250</ref> <ref>PMID:18310071</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Aubry, A.]]
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[[Category: Aubry, A]]
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[[Category: Branlant, G.]]
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[[Category: Branlant, G]]
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[[Category: Corbier, C.]]
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[[Category: Corbier, C]]
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[[Category: Didierjean, C.]]
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[[Category: Didierjean, C]]
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[[Category: Dubourg, H.]]
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[[Category: Dubourg, H]]
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[[Category: Stines-Chaumeil, C.]]
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[[Category: Stines-Chaumeil, C]]
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[[Category: Talfournier, F.]]
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[[Category: Talfournier, F]]
[[Category: Nad]]
[[Category: Nad]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]

Revision as of 06:15, 25 December 2014

Crystal structure of methylmalonate semialdehyde dehydrogenase from Bacillus subtilis

1t90, resolution 2.50Å

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