2ix7

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ix7]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IX7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IX7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ix7]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IX7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IX7 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CYS:CYSTEINE'>CYS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CYS:CYSTEINE'>CYS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ix7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ix7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ix7 RCSB], [http://www.ebi.ac.uk/pdbsum/2ix7 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ix7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ix7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ix7 RCSB], [http://www.ebi.ac.uk/pdbsum/2ix7 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MYO5A_MOUSE MYO5A_MOUSE]] Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation.<ref>PMID:22908308</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Lk3 transgenic mice]]
[[Category: Lk3 transgenic mice]]
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[[Category: Cohen, C.]]
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[[Category: Cohen, C]]
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[[Category: Gaucher, J F.]]
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[[Category: Gaucher, J F]]
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[[Category: Houdusse, A.]]
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[[Category: Houdusse, A]]
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[[Category: Krementsova, E.]]
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[[Category: Krementsova, E]]
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[[Category: Mui, S.]]
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[[Category: Mui, S]]
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[[Category: Trybus, K M.]]
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[[Category: Trybus, K M]]
[[Category: Actin-binding]]
[[Category: Actin-binding]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]

Revision as of 06:20, 25 December 2014

Structure of apo-calmodulin bound to unconventional myosin V

2ix7, resolution 2.50Å

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