This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4le8
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4le8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LE8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LE8 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4le8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LE8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LE8 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4leb|4leb]], [[4lee|4lee]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4leb|4leb]], [[4lee|4lee]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4le8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4le8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4le8 RCSB], [http://www.ebi.ac.uk/pdbsum/4le8 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4le8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4le8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4le8 RCSB], [http://www.ebi.ac.uk/pdbsum/4le8 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ALS3_CANAX ALS3_CANAX]] Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections. Necessary for C.albicans to bind to N-cadherin on endothelial cells and E-cadherin on oral epithelial cells and subsequent endocytosis by these cells (By similarity). | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Cota, E | + | [[Category: Cota, E]] |
| - | [[Category: Garnett, J A | + | [[Category: Garnett, J A]] |
| - | [[Category: Lin, J | + | [[Category: Lin, J]] |
[[Category: Adhesin]] | [[Category: Adhesin]] | ||
[[Category: Biofilm formation]] | [[Category: Biofilm formation]] | ||
Revision as of 06:24, 25 December 2014
Structure of the Als3 adhesin from Candida albicans, residues 1-299 (mature sequence)
| |||||||||||
