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2hd7
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2hd7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HD7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HD7 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2hd7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HD7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HD7 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ptk9 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ptk9 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hd7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hd7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hd7 RCSB], [http://www.ebi.ac.uk/pdbsum/2hd7 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hd7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hd7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hd7 RCSB], [http://www.ebi.ac.uk/pdbsum/2hd7 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TWF1_MOUSE TWF1_MOUSE]] Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles.<ref>PMID:9249064</ref> <ref>PMID:10669753</ref> <ref>PMID:15282541</ref> <ref>PMID:16511569</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Annila, A | + | [[Category: Annila, A]] |
| - | [[Category: Hellman, M H | + | [[Category: Hellman, M H]] |
| - | [[Category: Lappalainen, P | + | [[Category: Lappalainen, P]] |
| - | [[Category: Paavilainen, V O | + | [[Category: Paavilainen, V O]] |
| - | [[Category: Permi, P I | + | [[Category: Permi, P I]] |
[[Category: Actin binding protein]] | [[Category: Actin binding protein]] | ||
[[Category: Adf-h]] | [[Category: Adf-h]] | ||
[[Category: Contractile protein]] | [[Category: Contractile protein]] | ||
Revision as of 06:37, 25 December 2014
Solution structure of C-teminal domain of twinfilin-1.
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