2ymj

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ymj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ymj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ymj RCSB], [http://www.ebi.ac.uk/pdbsum/2ymj PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ymj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ymj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ymj RCSB], [http://www.ebi.ac.uk/pdbsum/2ymj PDBsum]</span></td></tr>
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== Function ==
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[[http://www.uniprot.org/uniprot/QKIA_XENLA QKIA_XENLA]] RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of some pre-mRNA. Acts as a translational repressor (By similarity). Essential for notochord development.<ref>PMID:9303534</ref>
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Revision as of 06:50, 25 December 2014

Solution structure of the QUA1 dimerization domain of pXqua, the Xenopus ortholog of Quaking.

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