3ls8
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ls8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ls8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ls8 RCSB], [http://www.ebi.ac.uk/pdbsum/3ls8 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ls8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ls8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ls8 RCSB], [http://www.ebi.ac.uk/pdbsum/3ls8 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PK3C3_HUMAN PK3C3_HUMAN]] Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.<ref>PMID:7628435</ref> <ref>PMID:14617358</ref> <ref>PMID:20208530</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
*[[Phosphoinositide 3-Kinases|Phosphoinositide 3-Kinases]] | *[[Phosphoinositide 3-Kinases|Phosphoinositide 3-Kinases]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 06:50, 25 December 2014
Crystal structure of human PIK3C3 in complex with 3-[4-(4-Morpholinyl)thieno[3,2-d]pyrimidin-2-yl]-phenol
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Categories: Homo sapiens | Phosphatidylinositol 3-kinase | Arrowsmith, C H | Berg, S Van den | Berglund, H | Bountra, C | Collins, R | Edwards, A M | Flodin, S | Flores, A | Graslund, S | Hammarstrom, M | Johansson, I | Karlberg, T | Kotenyova, T | Kraulis, P | Moche, M | Nordlund, P | Nyman, T | Persson, C | Structural genomic | Schuler, H | Schutz, P | Siponen, M I | Thorsell, A G | Tresaugues, L | Wahlberg, E | Weigelt, J | Welin, M | Wisniewska, M | Alpha/beta protein | Atp-binding | Compound 15e | Inhibitor | Kinase | Nucleotide-binding | Phosphatidylinositol | Phosphatidylinositol 3-kinase catalytic subunit type 3 | Phosphoprotein | Pik3c3 | Sgc | Sgc stockholm | Transferase
