2c2f
From Proteopedia
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| - | [[Image:2c2f.gif|left|200px]] | + | [[Image:2c2f.gif|left|200px]] |
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| - | '''DPS FROM DEINOCOCCUS RADIODURANS''' | + | {{Structure |
| + | |PDB= 2c2f |SIZE=350|CAPTION= <scene name='initialview01'>2c2f</scene>, resolution 1.61Å | ||
| + | |SITE= <scene name='pdbsite=AC1:Gol+Binding+Site+For+Chain+A'>AC1</scene> | ||
| + | |LIGAND= <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene> | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''DPS FROM DEINOCOCCUS RADIODURANS''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2C2F is a [ | + | 2C2F is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C2F OCA]. |
==Reference== | ==Reference== | ||
| - | The crystal structure of Deinococcus radiodurans Dps protein (DR2263) reveals the presence of a novel metal centre in the N terminus., Romao CV, Mitchell EP, McSweeney S, J Biol Inorg Chem. 2006 Oct;11(7):891-902. Epub 2006 Jul 20. PMID:[http:// | + | The crystal structure of Deinococcus radiodurans Dps protein (DR2263) reveals the presence of a novel metal centre in the N terminus., Romao CV, Mitchell EP, McSweeney S, J Biol Inorg Chem. 2006 Oct;11(7):891-902. Epub 2006 Jul 20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16855817 16855817] |
[[Category: Deinococcus radiodurans]] | [[Category: Deinococcus radiodurans]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: SO4]] | [[Category: SO4]] | ||
[[Category: ZN]] | [[Category: ZN]] | ||
| - | [[Category: deinococcus | + | [[Category: deinococcus radioduran]] |
[[Category: dna-binding protein]] | [[Category: dna-binding protein]] | ||
| - | [[Category: | + | [[Category: dp]] |
[[Category: iron]] | [[Category: iron]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:09:55 2008'' |
Revision as of 14:09, 20 March 2008
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| , resolution 1.61Å | |||||||
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| Sites: | |||||||
| Ligands: | , , and | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
DPS FROM DEINOCOCCUS RADIODURANS
Overview
The crystal structure of a DNA-binding protein from starved cells (Dps) (DR2263) from Deinococcus radiodurans was determined in two states: a native form, to 1.1-A resolution, and one soaked in an iron solution, to 1.6-A resolution. In comparison with other Dps proteins, DR2263 has an extended N-terminal extension, in both structures presented here, a novel metal binding site was identified in this N-terminal extension and was assigned to bound zinc. The zinc is tetrahedrally coordinated and the ligands, that belong to the N-terminal extension, are two histidines, one glutamate and one aspartate residue, which are unique to this protein within the Dps family. In the iron-soaked crystal structure, a total of three iron sites per monomer were found: one site corresponds to the ferroxidase centre with structural similarities to those found in other Dps family members; the two other sites are located on the two different threefold axes corresponding to small pores in the Dps sphere, which may possibly form the entrance and exit channels for iron storage.
About this Structure
2C2F is a Single protein structure of sequence from Deinococcus radiodurans. Full crystallographic information is available from OCA.
Reference
The crystal structure of Deinococcus radiodurans Dps protein (DR2263) reveals the presence of a novel metal centre in the N terminus., Romao CV, Mitchell EP, McSweeney S, J Biol Inorg Chem. 2006 Oct;11(7):891-902. Epub 2006 Jul 20. PMID:16855817
Page seeded by OCA on Thu Mar 20 16:09:55 2008
Categories: Deinococcus radiodurans | Single protein | Mcsweeney, S. | Mitchell, E. | Romao, C V. | FE | GOL | SO4 | ZN | Deinococcus radioduran | Dna-binding protein | Dp | Iron
