3cz3

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cz3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cz3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cz3 RCSB], [http://www.ebi.ac.uk/pdbsum/3cz3 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cz3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cz3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cz3 RCSB], [http://www.ebi.ac.uk/pdbsum/3cz3 PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ORF2B_TAV ORF2B_TAV]] Acts as suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Forms a homodimer to measure siRNA duplex in a length-preferencemode. Binds to both siRNA duplexes (19bp) and long siRNA duplexes (30bp).<ref>PMID:8291242</ref> <ref>PMID:9010309</ref> <ref>PMID:10329615</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Tomato aspermy virus]]
[[Category: Tomato aspermy virus]]
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[[Category: Ding, S W.]]
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[[Category: Ding, S W]]
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[[Category: Li, F.]]
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[[Category: Li, F]]
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[[Category: Ma, J B.]]
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[[Category: Ma, J B]]
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[[Category: Patel, D J.]]
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[[Category: Patel, D J]]
[[Category: Nucleus]]
[[Category: Nucleus]]
[[Category: Protein-dsrna complex]]
[[Category: Protein-dsrna complex]]
[[Category: Suppressor of rna silencing]]
[[Category: Suppressor of rna silencing]]
[[Category: Viral protein-rna complex]]
[[Category: Viral protein-rna complex]]

Revision as of 07:04, 25 December 2014

Crystal structure of Tomato Aspermy Virus 2b in complex with siRNA

3cz3, resolution 3.23Å

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