1kkd
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1kkd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KKD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KKD FirstGlance]. <br> | <table><tr><td colspan='2'>[[1kkd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KKD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KKD FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1g4y|1g4y]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1g4y|1g4y]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SK2 (KCNN2) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SK2 (KCNN2) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kkd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kkd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kkd RCSB], [http://www.ebi.ac.uk/pdbsum/1kkd PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kkd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kkd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kkd RCSB], [http://www.ebi.ac.uk/pdbsum/1kkd PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/KCNN2_RAT KCNN2_RAT]] Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
| - | [[Category: Adelman, J P | + | [[Category: Adelman, J P]] |
| - | [[Category: Bentrop, D | + | [[Category: Bentrop, D]] |
| - | [[Category: Bildl, W | + | [[Category: Bildl, W]] |
| - | [[Category: Fakler, B | + | [[Category: Fakler, B]] |
| - | [[Category: Kloecker, N | + | [[Category: Kloecker, N]] |
| - | [[Category: Neumann, H | + | [[Category: Neumann, H]] |
| - | [[Category: Rivard, A F | + | [[Category: Rivard, A F]] |
| - | [[Category: Schulte, U | + | [[Category: Schulte, U]] |
| - | [[Category: Weitz, D | + | [[Category: Weitz, D]] |
| - | [[Category: Wissmann, R | + | [[Category: Wissmann, R]] |
[[Category: Channel gating]] | [[Category: Channel gating]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
[[Category: Small-conductance calcium-activated potassium channel]] | [[Category: Small-conductance calcium-activated potassium channel]] | ||
Revision as of 07:05, 25 December 2014
Solution structure of the calmodulin binding domain (CaMBD) of small conductance Ca2+-activated potassium channels (SK2)
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