3rks

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3rks]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Manihot_esculenta Manihot esculenta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RKS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RKS FirstGlance]. <br>
<table><tr><td colspan='2'>[[3rks]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Manihot_esculenta Manihot esculenta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RKS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RKS FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3rkt|3rkt]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3rkt|3rkt]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HNL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3983 Manihot esculenta])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HNL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3983 Manihot esculenta])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydroxynitrilase Hydroxynitrilase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.37 4.1.2.37] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydroxynitrilase Hydroxynitrilase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.37 4.1.2.37] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rks FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rks OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rks RCSB], [http://www.ebi.ac.uk/pdbsum/3rks PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rks FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rks OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rks RCSB], [http://www.ebi.ac.uk/pdbsum/3rks PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/HNL_MANES HNL_MANES]] Involved in cyanogenesis, the release of HCN from injured tissues. Decomposes a varieties of (R) or (S) cyanohydrins into HCN and the corresponding aldehydes and ketones. The natural substrate of this enzyme is (S)-acetone cyanohydrin.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Hydroxynitrilase]]
[[Category: Hydroxynitrilase]]
[[Category: Manihot esculenta]]
[[Category: Manihot esculenta]]
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[[Category: Asano, Y.]]
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[[Category: Asano, Y]]
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[[Category: Cielo, C B.C.]]
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[[Category: Cielo, C B.C]]
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[[Category: Dadashipour, M.]]
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[[Category: Dadashipour, M]]
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[[Category: Komeda, H.]]
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[[Category: Komeda, H]]
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[[Category: Mizushima, T.]]
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[[Category: Mizushima, T]]
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[[Category: Suzuki, A.]]
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[[Category: Suzuki, A]]
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[[Category: Yamane, T.]]
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[[Category: Yamane, T]]
[[Category: Acetate]]
[[Category: Acetate]]
[[Category: Acetate cyanohydrin]]
[[Category: Acetate cyanohydrin]]

Revision as of 07:06, 25 December 2014

Crystal Structure of the Manihot esculenta Hydroxynitrile Lyase (MeHNL) K176P mutant

3rks, resolution 2.50Å

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