3ge1
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3ge1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_col Staphylococcus aureus subsp. aureus col]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GE1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GE1 FirstGlance]. <br> | <table><tr><td colspan='2'>[[3ge1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_col Staphylococcus aureus subsp. aureus col]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GE1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GE1 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3g25|3g25]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3g25|3g25]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">glpK, SACOL1320 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93062 Staphylococcus aureus subsp. aureus COL])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">glpK, SACOL1320 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93062 Staphylococcus aureus subsp. aureus COL])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycerol_kinase Glycerol kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.30 2.7.1.30] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycerol_kinase Glycerol kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.30 2.7.1.30] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ge1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ge1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ge1 RCSB], [http://www.ebi.ac.uk/pdbsum/3ge1 PDBsum], [http://www.topsan.org/Proteins/CSGID/3ge1 TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ge1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ge1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ge1 RCSB], [http://www.ebi.ac.uk/pdbsum/3ge1 PDBsum], [http://www.topsan.org/Proteins/CSGID/3ge1 TOPSAN]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GLPK_STAAC GLPK_STAAC]] Key enzsyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate (By similarity).[HAMAP-Rule:MF_00186] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Glycerol kinase]] | [[Category: Glycerol kinase]] | ||
[[Category: Staphylococcus aureus subsp. aureus col]] | [[Category: Staphylococcus aureus subsp. aureus col]] | ||
| - | [[Category: Anderson, W F | + | [[Category: Anderson, W F]] |
| - | [[Category: Brunzelle, J | + | [[Category: Brunzelle, J]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Minasov, G | + | [[Category: Minasov, G]] |
| - | [[Category: Onopriyenko, O | + | [[Category: Onopriyenko, O]] |
| - | [[Category: Peterson, S N | + | [[Category: Peterson, S N]] |
| - | [[Category: Savchenko, A | + | [[Category: Savchenko, A]] |
| - | [[Category: Skarina, T | + | [[Category: Skarina, T]] |
[[Category: Adp]] | [[Category: Adp]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
| - | [[Category: Center for structural genomics of infectious disease]] | ||
[[Category: Csgid]] | [[Category: Csgid]] | ||
[[Category: Glycerol]] | [[Category: Glycerol]] | ||
| - | [[Category: Glycerol kinase]] | ||
[[Category: Glycerol metabolism]] | [[Category: Glycerol metabolism]] | ||
[[Category: Idp00743]] | [[Category: Idp00743]] | ||
[[Category: Kinase]] | [[Category: Kinase]] | ||
[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 07:10, 25 December 2014
2.7 Angstrom Crystal Structure of Glycerol Kinase (glpK) from Staphylococcus aureus in Complex with ADP and Glycerol
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Categories: Glycerol kinase | Staphylococcus aureus subsp. aureus col | Anderson, W F | Brunzelle, J | Structural genomic | Minasov, G | Onopriyenko, O | Peterson, S N | Savchenko, A | Skarina, T | Adp | Atp-binding | Csgid | Glycerol | Glycerol metabolism | Idp00743 | Kinase | Nucleotide-binding | Transferase
