3t0l
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t0l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t0l RCSB], [http://www.ebi.ac.uk/pdbsum/3t0l PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t0l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t0l RCSB], [http://www.ebi.ac.uk/pdbsum/3t0l PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 07:15, 25 December 2014
Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening
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