3pso
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pso OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pso RCSB], [http://www.ebi.ac.uk/pdbsum/3pso PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pso OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pso RCSB], [http://www.ebi.ac.uk/pdbsum/3pso PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/VPS29_MOUSE VPS29_MOUSE]] Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro). | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 07:16, 25 December 2014
Crystal structure of mouse VPS29 complexed with Zn2+
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Categories: Mus musculus | Chhabra, S | Collins, B | Ghai, R | Norwood, S | Shaw, D | Swarbrick, J | Valkov, E | Hydrolase | Membrane trafficking | Phosphatase fold | Scaffold | Snx1 | Tbc1d5 | Vps35
