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2xwc
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xwc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xwc RCSB], [http://www.ebi.ac.uk/pdbsum/2xwc PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xwc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xwc RCSB], [http://www.ebi.ac.uk/pdbsum/2xwc PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/P73_HUMAN P73_HUMAN]] Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.<ref>PMID:11753569</ref> <ref>PMID:10203277</ref> <ref>PMID:18174154</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 07:20, 25 December 2014
Crystal structure of the DNA binding domain of human TP73 refined at 1.8 A resolution
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