2pnt

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2pnt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PNT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PNT FirstGlance]. <br>
<table><tr><td colspan='2'>[[2pnt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PNT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PNT FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GRASP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GRASP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pnt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pnt RCSB], [http://www.ebi.ac.uk/pdbsum/2pnt PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pnt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pnt RCSB], [http://www.ebi.ac.uk/pdbsum/2pnt PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/GRASP_HUMAN GRASP_HUMAN]] Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Arrowsmith, C H]]
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[[Category: Bray, J.]]
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[[Category: Bray, J]]
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[[Category: Cooper, C.]]
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[[Category: Cooper, C]]
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[[Category: Delft, F von.]]
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[[Category: Delft, F von]]
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[[Category: Doyle, D A.]]
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[[Category: Doyle, D A]]
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[[Category: Edwards, A.]]
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[[Category: Edwards, A]]
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[[Category: Elkins, J.]]
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[[Category: Elkins, J]]
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[[Category: Gileadi, C.]]
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[[Category: Gileadi, C]]
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[[Category: Gileadi, O.]]
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[[Category: Gileadi, O]]
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[[Category: Papagrigoriou, E.]]
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[[Category: Papagrigoriou, E]]
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[[Category: Pike, A C.W.]]
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[[Category: Pike, A C.W]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Structural genomic]]
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[[Category: Sundstrom, M.]]
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[[Category: Sundstrom, M]]
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[[Category: Ugochukwu, E.]]
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[[Category: Ugochukwu, E]]
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[[Category: Umeano, C.]]
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[[Category: Umeano, C]]
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[[Category: Uppenberg, J.]]
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[[Category: Uppenberg, J]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt, J]]
[[Category: Scaffold protein]]
[[Category: Scaffold protein]]
[[Category: Sgc]]
[[Category: Sgc]]
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[[Category: Structural genomic]]
 
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[[Category: Structural genomics consortium]]
 
[[Category: Unknown function]]
[[Category: Unknown function]]

Revision as of 07:22, 25 December 2014

Crystal structure of the PDZ domain of human GRASP (GRP1) in complex with the C-terminal peptide of the metabotropic glutamate receptor type 1

2pnt, resolution 2.15Å

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