2xf1
From Proteopedia
(Difference between revisions)
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<StructureSection load='2xf1' size='340' side='right' caption='[[2xf1]], [[Resolution|resolution]] 1.96Å' scene=''> | <StructureSection load='2xf1' size='340' side='right' caption='[[2xf1]], [[Resolution|resolution]] 1.96Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2xf1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XF1 OCA]. <br> | + | <table><tr><td colspan='2'>[[2xf1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XF1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XF1 FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr> | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr> |
| - | <tr | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xf1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xf1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xf1 RCSB], [http://www.ebi.ac.uk/pdbsum/2xf1 PDBsum]</span></td></tr> |
| - | + | </table> | |
| - | <table> | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/CADF1_PLAF7 CADF1_PLAF7]] Not involved in actin polymerisation, instead functions to stimulate nucleotide exchange on monomeric actin and influence turnover of the small amount of cytosolic actin microfilaments. Essential for erythrocytic schizogony (By similarity).[UniProtKB:P86292] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Crystal structures explain functional differences in the two actin depolymerization factors of the malaria parasite.,Singh BK, Sattler JM, Chatterjee M, Huttu J, Schuler H, Kursula I J Biol Chem. 2011 Aug 12;286(32):28256-64. PMID:21832095<ref>PMID:21832095</ref> | Crystal structures explain functional differences in the two actin depolymerization factors of the malaria parasite.,Singh BK, Sattler JM, Chatterjee M, Huttu J, Schuler H, Kursula I J Biol Chem. 2011 Aug 12;286(32):28256-64. PMID:21832095<ref>PMID:21832095</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Plasmodium falciparum]] | [[Category: Plasmodium falciparum]] | ||
| - | [[Category: Chatterjee, M | + | [[Category: Chatterjee, M]] |
| - | [[Category: Huttu, J | + | [[Category: Huttu, J]] |
| - | [[Category: Kursula, I | + | [[Category: Kursula, I]] |
| - | [[Category: Sattler, J M | + | [[Category: Sattler, J M]] |
| - | [[Category: Schueler, H | + | [[Category: Schueler, H]] |
| - | [[Category: Singh, B K | + | [[Category: Singh, B K]] |
[[Category: Actin-binding protein]] | [[Category: Actin-binding protein]] | ||
[[Category: Cytoskeleton]] | [[Category: Cytoskeleton]] | ||
Revision as of 07:30, 25 December 2014
CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM ACTIN DEPOLYMERIZATION FACTOR 1
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