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3f7v

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3f7v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f7v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3f7v RCSB], [http://www.ebi.ac.uk/pdbsum/3f7v PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3f7v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f7v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3f7v RCSB], [http://www.ebi.ac.uk/pdbsum/3f7v PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/KCSA_STRLI KCSA_STRLI]] Acts as a pH-gated potassium ion channel; changing the cytosolic pH from 7 to 4 opens the channel, although it is not clear if this is the physiological stimulus for channel opening. Monovalent cation preference is K(+) > Rb(+) > NH4(+) >> Na(+) > Li(+).<ref>PMID:7489706</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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*[[Antibody|Antibody]]
*[[Antibody|Antibody]]
*[[Potassium Channel|Potassium Channel]]
*[[Potassium Channel|Potassium Channel]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>

Revision as of 07:31, 25 December 2014

KcsA Potassium channel in the open-inactivated state with 23 A opening at T112

3f7v, resolution 3.20Å

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