4hnw
From Proteopedia
(Difference between revisions)
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| - | + | ==The NatA Acetyltransferase Complex Bound To Inositol Hexakisphosphate== | |
| - | + | <StructureSection load='4hnw' size='340' side='right' caption='[[4hnw]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | ==Function== | + | <table><tr><td colspan='2'>[[4hnw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HNW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HNW FirstGlance]. <br> |
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IHP:INOSITOL+HEXAKISPHOSPHATE'>IHP</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4hnx|4hnx]], [[4hny|4hny]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NAT1, AAA1, YDL040C, D2720 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast]), ARD1, YHR013C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide_alpha-N-acetyltransferase Peptide alpha-N-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.88 2.3.1.88] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hnw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hnw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hnw RCSB], [http://www.ebi.ac.uk/pdbsum/4hnw PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
[[http://www.uniprot.org/uniprot/NAT1_YEAST NAT1_YEAST]] Non-catalytic component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover. NAT1 anchors ARD1 and NAT5 to the ribosome and may present the N termini of nascent polypeptides for acetylation.<ref>PMID:1600941</ref> <ref>PMID:14517307</ref> [[http://www.uniprot.org/uniprot/ARD1_YEAST ARD1_YEAST]] Catalytic component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover.<ref>PMID:1600941</ref> | [[http://www.uniprot.org/uniprot/NAT1_YEAST NAT1_YEAST]] Non-catalytic component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover. NAT1 anchors ARD1 and NAT5 to the ribosome and may present the N termini of nascent polypeptides for acetylation.<ref>PMID:1600941</ref> <ref>PMID:14517307</ref> [[http://www.uniprot.org/uniprot/ARD1_YEAST ARD1_YEAST]] Catalytic component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover.<ref>PMID:1600941</ref> | ||
| - | + | == References == | |
| - | == | + | <references/> |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Baker's yeast]] | |
| - | <references | + | |
[[Category: Peptide alpha-N-acetyltransferase]] | [[Category: Peptide alpha-N-acetyltransferase]] | ||
| - | [[Category: Dollins, D E | + | [[Category: Dollins, D E]] |
| - | [[Category: Endo-Streeter, S T | + | [[Category: Endo-Streeter, S T]] |
| - | [[Category: IV, C W.Pemble | + | [[Category: IV, C W.Pemble]] |
| - | [[Category: Immormino, R M | + | [[Category: Immormino, R M]] |
| - | [[Category: Neubauer, J L | + | [[Category: Neubauer, J L]] |
| - | [[Category: York, J D | + | [[Category: York, J D]] |
[[Category: Gnat/tpr]] | [[Category: Gnat/tpr]] | ||
[[Category: Inositol hexakisphosphate]] | [[Category: Inositol hexakisphosphate]] | ||
[[Category: N-terminal acetyltransferase]] | [[Category: N-terminal acetyltransferase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 07:32, 25 December 2014
The NatA Acetyltransferase Complex Bound To Inositol Hexakisphosphate
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