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2van
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2van]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VAN FirstGlance]. <br> | <table><tr><td colspan='2'>[[2van]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VAN FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1bno|1bno]], [[1bpb|1bpb]], [[1bpe|1bpe]], [[1dk2|1dk2]], [[1huo|1huo]], [[1huz|1huz]], [[1zqv|1zqv]], [[1bnp|1bnp]], [[1bpd|1bpd]], [[1dk3|1dk3]], [[1jn3|1jn3]], [[1nom|1nom]], [[1rpl|1rpl]], [[1zqu|1zqu]], [[1zqw|1zqw]], [[1zqx|1zqx]], [[1zqy|1zqy]], [[1zqz|1zqz]], [[2bpc|2bpc]], [[2bpf|2bpf]], [[2bpg|2bpg]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1bno|1bno]], [[1bpb|1bpb]], [[1bpe|1bpe]], [[1dk2|1dk2]], [[1huo|1huo]], [[1huz|1huz]], [[1zqv|1zqv]], [[1bnp|1bnp]], [[1bpd|1bpd]], [[1dk3|1dk3]], [[1jn3|1jn3]], [[1nom|1nom]], [[1rpl|1rpl]], [[1zqu|1zqu]], [[1zqw|1zqw]], [[1zqx|1zqx]], [[1zqy|1zqy]], [[1zqz|1zqz]], [[2bpc|2bpc]], [[2bpf|2bpf]], [[2bpg|2bpg]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2van FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2van OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2van RCSB], [http://www.ebi.ac.uk/pdbsum/2van PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2van FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2van OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2van RCSB], [http://www.ebi.ac.uk/pdbsum/2van PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DPOLB_RAT DPOLB_RAT]] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
| - | [[Category: Chan, H | + | [[Category: Chan, H]] |
| - | [[Category: Chou, C | + | [[Category: Chou, C]] |
| - | [[Category: Niebuhr, M | + | [[Category: Niebuhr, M]] |
| - | [[Category: Tang, K | + | [[Category: Tang, K]] |
| - | [[Category: Tsai, M | + | [[Category: Tsai, M]] |
| - | [[Category: Tung, C | + | [[Category: Tung, C]] |
[[Category: Dna damage]] | [[Category: Dna damage]] | ||
[[Category: Dna repair]] | [[Category: Dna repair]] | ||
Revision as of 07:57, 25 December 2014
NUCLEOTIDYL TRANSFER MECHANISM OF MISMATCHED DNTP INCORPORATION BY DNA POLYMERASE B BY STRUCTURAL AND KINETIC ANALYSES
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