1j6x

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1j6x]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J6X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J6X FirstGlance]. <br>
<table><tr><td colspan='2'>[[1j6x]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J6X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J6X FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j6x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1j6x RCSB], [http://www.ebi.ac.uk/pdbsum/1j6x PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j6x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1j6x RCSB], [http://www.ebi.ac.uk/pdbsum/1j6x PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/LUXS_HELPJ LUXS_HELPJ]] Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Helicobacter pylori]]
[[Category: Helicobacter pylori]]
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[[Category: Bergseid, M G.]]
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[[Category: Bergseid, M G]]
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[[Category: Buchanan, S G.]]
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[[Category: Buchanan, S G]]
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[[Category: Furlong, E B.]]
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[[Category: Furlong, E B]]
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[[Category: Lewis, H A.]]
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[[Category: Lewis, H A]]
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[[Category: Sanderson, W E.]]
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[[Category: Sanderson, W E]]
[[Category: Alpha-beta fold]]
[[Category: Alpha-beta fold]]
[[Category: Signaling protein]]
[[Category: Signaling protein]]

Revision as of 08:05, 25 December 2014

CRYSTAL STRUCTURE OF HELICOBACTER PYLORI LUXS

1j6x, resolution 2.38Å

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