3q7p

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q7p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q7p RCSB], [http://www.ebi.ac.uk/pdbsum/3q7p PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q7p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q7p RCSB], [http://www.ebi.ac.uk/pdbsum/3q7p PDBsum]</span></td></tr>
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== Function ==
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[[http://www.uniprot.org/uniprot/RAD_HUMAN RAD_HUMAN]] May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane (By similarity). Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D.<ref>PMID:18056528</ref>
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Revision as of 08:36, 25 December 2014

Crystal Structure of Rad G-domain-GTP Analog Complex

3q7p, resolution 2.50Å

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