4hd9
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hd9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hd9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hd9 RCSB], [http://www.ebi.ac.uk/pdbsum/4hd9 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hd9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hd9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hd9 RCSB], [http://www.ebi.ac.uk/pdbsum/4hd9 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MADCA_HUMAN MADCA_HUMAN]] Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 08:40, 25 December 2014
Crystal structure of native human MAdCAM-1 D1D2 domain
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