3qh2

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3qh2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QH2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QH2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3qh2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QH2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QH2 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3NM:4-METHYL-5-[2-(PHOSPHONOOXY)ETHYL]-1,3-THIAZOLE-2-CARBOXYLIC+ACID'>3NM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3NM:4-METHYL-5-[2-(PHOSPHONOOXY)ETHYL]-1,3-THIAZOLE-2-CARBOXYLIC+ACID'>3NM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tenI, BSU11660 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tenI, BSU11660 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qh2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qh2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qh2 RCSB], [http://www.ebi.ac.uk/pdbsum/3qh2 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qh2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qh2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qh2 RCSB], [http://www.ebi.ac.uk/pdbsum/3qh2 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/TENI_BACSU TENI_BACSU]] Reduces the stimulatory effect of the TenA transcriptional activator on production of certain extracellular enzymes. Is not an essential protein, but affects the sporulation frequency.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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A Missing Enzyme in Thiamin Thiazole Biosynthesis: Identification of TenI as a Thiazole Tautomerase.,Hazra AB, Han Y, Chatterjee A, Zhang Y, Lai RY, Ealick SE, Begley TP J Am Chem Soc. 2011 May 2. PMID:21534620<ref>PMID:21534620</ref>
A Missing Enzyme in Thiamin Thiazole Biosynthesis: Identification of TenI as a Thiazole Tautomerase.,Hazra AB, Han Y, Chatterjee A, Zhang Y, Lai RY, Ealick SE, Begley TP J Am Chem Soc. 2011 May 2. PMID:21534620<ref>PMID:21534620</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Begley, T P.]]
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[[Category: Begley, T P]]
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[[Category: Chatterjee, A.]]
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[[Category: Chatterjee, A]]
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[[Category: Ealick, S E.]]
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[[Category: Ealick, S E]]
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[[Category: Han, Y.]]
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[[Category: Han, Y]]
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[[Category: Hazra, A.]]
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[[Category: Hazra, A]]
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[[Category: Lai, R.]]
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[[Category: Lai, R]]
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[[Category: Zhang, Y.]]
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[[Category: Zhang, Y]]
[[Category: Alpha-beta barrel]]
[[Category: Alpha-beta barrel]]
[[Category: Isomerase]]
[[Category: Isomerase]]

Revision as of 08:41, 25 December 2014

Crystal structure of TenI from Bacillus subtilis complexed with product cThz-P

3qh2, resolution 2.23Å

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