4p3c
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p3c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p3c RCSB], [http://www.ebi.ac.uk/pdbsum/4p3c PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p3c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p3c RCSB], [http://www.ebi.ac.uk/pdbsum/4p3c PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MMP14_HUMAN MMP14_HUMAN]] Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15.<ref>PMID:20837484</ref> <ref>PMID:22065321</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 08:48, 25 December 2014
MT1-MMP:Fab complex (Form I)
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