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4l6c
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l6c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l6c RCSB], [http://www.ebi.ac.uk/pdbsum/4l6c PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l6c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l6c RCSB], [http://www.ebi.ac.uk/pdbsum/4l6c PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NT5M_HUMAN NT5M_HUMAN]] Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Brynda, J | + | [[Category: Brynda, J]] |
| - | [[Category: Pachl, P | + | [[Category: Pachl, P]] |
| - | [[Category: Rezacova, P | + | [[Category: Rezacova, P]] |
[[Category: 5'-nucleotidase]] | [[Category: 5'-nucleotidase]] | ||
[[Category: Dephosphorylation]] | [[Category: Dephosphorylation]] | ||
Revision as of 08:58, 25 December 2014
Crystal structure of human mitochondrial deoxyribonucleotidase in complex with the inhibitor pib-t
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