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3k2z
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k2z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3k2z RCSB], [http://www.ebi.ac.uk/pdbsum/3k2z PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k2z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3k2z RCSB], [http://www.ebi.ac.uk/pdbsum/3k2z PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LEXA_THEMA LEXA_THEMA]] Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 08:58, 25 December 2014
Crystal structure of a LexA protein from Thermotoga maritima
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