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1pmd

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1pmd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PMD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PMD FirstGlance]. <br>
<table><tr><td colspan='2'>[[1pmd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PMD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PMD FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pmd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1pmd RCSB], [http://www.ebi.ac.uk/pdbsum/1pmd PDBsum]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pmd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1pmd RCSB], [http://www.ebi.ac.uk/pdbsum/1pmd PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PBPX_STRPN PBPX_STRPN]] Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. Beta-lactams inactivate the PBPs by acylating an essential serine residue in the active site of these proteins.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Streptococcus pneumoniae]]
[[Category: Streptococcus pneumoniae]]
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[[Category: Dideberg, O.]]
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[[Category: Dideberg, O]]
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[[Category: Mouz, N.]]
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[[Category: Mouz, N]]
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[[Category: Pares, S.]]
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[[Category: Pares, S]]
[[Category: Cell wall]]
[[Category: Cell wall]]
[[Category: Peptidoglycan synthesis]]
[[Category: Peptidoglycan synthesis]]
[[Category: Resistance]]
[[Category: Resistance]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]

Revision as of 09:00, 25 December 2014

PENICILLIN-BINDING PROTEIN 2X (PBP-2X)

1pmd, resolution 3.50Å

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