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4dlo

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4dlo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DLO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DLO FirstGlance]. <br>
<table><tr><td colspan='2'>[[4dlo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DLO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DLO FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=FUL:BETA-L-FUCOSE'>FUL</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=FUL:BETA-L-FUCOSE'>FUL</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4dlq|4dlq]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4dlq|4dlq]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAI3, KIAA0550 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAI3, KIAA0550 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dlo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dlo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dlo RCSB], [http://www.ebi.ac.uk/pdbsum/4dlo PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dlo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dlo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dlo RCSB], [http://www.ebi.ac.uk/pdbsum/4dlo PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/BAI3_HUMAN BAI3_HUMAN]] May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Might be involved in angiogenesis inhibition and suppression of glioblastoma.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Arac, D.]]
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[[Category: Arac, D]]
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[[Category: Bolliger, M F.]]
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[[Category: Bolliger, M F]]
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[[Category: Boucard, A A.]]
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[[Category: Boucard, A A]]
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[[Category: Brunger, A T.]]
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[[Category: Brunger, A T]]
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[[Category: Nguyen, J.]]
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[[Category: Nguyen, J]]
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[[Category: Soltis, M.]]
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[[Category: Soltis, M]]
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[[Category: Sudhof, T C.]]
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[[Category: Sudhof, T C]]
[[Category: Autoproteolytic fold]]
[[Category: Autoproteolytic fold]]
[[Category: Extracellular]]
[[Category: Extracellular]]

Revision as of 09:02, 25 December 2014

Crystal structure of the GAIN and HormR domains of brain angiogenesis inhibitor 3 (BAI3)

4dlo, resolution 2.30Å

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