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2azs

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2azs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AZS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AZS FirstGlance]. <br>
<table><tr><td colspan='2'>[[2azs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AZS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AZS FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2a36|2a36]], [[2a37|2a37]], [[2azv|2azv]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2a36|2a36]], [[2a37|2a37]], [[2azv|2azv]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">drk, E sev 2B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">drk, E sev 2B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2azs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2azs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2azs RCSB], [http://www.ebi.ac.uk/pdbsum/2azs PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2azs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2azs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2azs RCSB], [http://www.ebi.ac.uk/pdbsum/2azs PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/DRK_DROME DRK_DROME]] Required for proper signaling by sevenless. May act to stimulate the ability of Sos to catalyze Ras1 activation by linking sevenless and Sos in a signaling complex.<ref>PMID:8462097</ref> <ref>PMID:8462098</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
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[[Category: Bezsonova, I.]]
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[[Category: Bezsonova, I]]
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[[Category: Choy, W Y.]]
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[[Category: Choy, W Y]]
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[[Category: Forman-Kay, J D.]]
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[[Category: Forman-Kay, J D]]
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[[Category: Singer, A U.]]
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[[Category: Singer, A U]]
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[[Category: Tollinger, M.]]
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[[Category: Tollinger, M]]
[[Category: Drk]]
[[Category: Drk]]
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[[Category: Drosophila melanogaster]]
 
[[Category: Sh3 fragment]]
[[Category: Sh3 fragment]]
[[Category: Signaling protein]]
[[Category: Signaling protein]]

Revision as of 09:12, 25 December 2014

NMR structure of the N-terminal SH3 domain of Drk (calculated without NOE restraints)

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