1pcf
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1pcf]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PCF FirstGlance]. <br> | <table><tr><td colspan='2'>[[1pcf]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PCF FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pcf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1pcf RCSB], [http://www.ebi.ac.uk/pdbsum/1pcf PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pcf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1pcf RCSB], [http://www.ebi.ac.uk/pdbsum/1pcf PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TCP4_HUMAN TCP4_HUMAN]] General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).<ref>PMID:8062392</ref> <ref>PMID:8062391</ref> <ref>PMID:7628453</ref> <ref>PMID:9482861</ref> <ref>PMID:16689930</ref> <ref>PMID:9360603</ref> <ref>PMID:16605275</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Brandsen, J | + | [[Category: Brandsen, J]] |
| - | [[Category: Gros, P | + | [[Category: Gros, P]] |
[[Category: Nuclear protein]] | [[Category: Nuclear protein]] | ||
[[Category: Ssdna binding]] | [[Category: Ssdna binding]] | ||
Revision as of 09:13, 25 December 2014
HUMAN TRANSCRIPTIONAL COACTIVATOR PC4 C-TERMINAL DOMAIN
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