4nwc
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nwc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nwc RCSB], [http://www.ebi.ac.uk/pdbsum/4nwc PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nwc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nwc RCSB], [http://www.ebi.ac.uk/pdbsum/4nwc PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GRIK3_RAT GRIK3_RAT]] Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA.<ref>PMID:21907808</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Frydenvang, K | + | [[Category: Frydenvang, K]] |
| - | [[Category: Gajhede, M | + | [[Category: Gajhede, M]] |
| - | [[Category: Kastrup, J S | + | [[Category: Kastrup, J S]] |
| - | [[Category: Larsen, A P | + | [[Category: Larsen, A P]] |
| - | [[Category: Venskutonyte, R | + | [[Category: Venskutonyte, R]] |
[[Category: Agonist]] | [[Category: Agonist]] | ||
[[Category: Ionotropic glutamate receptor]] | [[Category: Ionotropic glutamate receptor]] | ||
Revision as of 09:19, 25 December 2014
Crystal structure of the GluK3 ligand-binding domain (S1S2) in complex with the agonist (2S,4R)-4-(3-Methoxy-3-oxopropyl)glutamic acid at 2.01 A resolution.
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