3e7v
From Proteopedia
(Difference between revisions)
| Line 8: | Line 8: | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3e7v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e7v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3e7v RCSB], [http://www.ebi.ac.uk/pdbsum/3e7v PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3e7v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e7v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3e7v RCSB], [http://www.ebi.ac.uk/pdbsum/3e7v PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HASP_HUMAN HASP_HUMAN]] Serine/threonine-protein kinase that phosphorylates histone H3 at 'Ser-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.<ref>PMID:11228240</ref> <ref>PMID:15681610</ref> <ref>PMID:17084365</ref> <ref>PMID:20705812</ref> <ref>PMID:20929775</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 21: | Line 23: | ||
==See Also== | ==See Also== | ||
*[[Serine/threonine protein kinase|Serine/threonine protein kinase]] | *[[Serine/threonine protein kinase|Serine/threonine protein kinase]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 09:27, 25 December 2014
Crystal Structure of Human Haspin with a pyrazolo-pyrimidine ligand
| |||||||||||
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Arrowsmith, C H | Bountra, C | Burgess-Brown, N | Delft, F Von | Edwards, A M | Eswaran, J | Fedorov, O | Filippakopoulos, P | Keates, T | Knapp, S | Pike, A C.W | Structural genomic | Wickstroem, M | Atp-binding | Cell cycle | Chromatin regulator | Haploid germ cell specific nuclear protein kinase | Haspin | Kinase | Magnesium | Nucleotide-binding | Nucleus | Phosphoprotein | Serine/threonine-protein kinase | Sgc | Transferase
