This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1z2u
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1z2u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z2U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z2U FirstGlance]. <br> | <table><tr><td colspan='2'>[[1z2u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z2U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z2U FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BU3:(R,R)-2,3-BUTANEDIOL'>BU3</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BU3:(R,R)-2,3-BUTANEDIOL'>BU3</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ubc-2, let-70 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 Caenorhabditis elegans])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ubc-2, let-70 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 Caenorhabditis elegans])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ubiquitin--protein_ligase Ubiquitin--protein ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.19 6.3.2.19] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ubiquitin--protein_ligase Ubiquitin--protein ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.19 6.3.2.19] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z2u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z2u RCSB], [http://www.ebi.ac.uk/pdbsum/1z2u PDBsum], [http://www.topsan.org/Proteins/SECSG/1z2u TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z2u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z2u RCSB], [http://www.ebi.ac.uk/pdbsum/1z2u PDBsum], [http://www.topsan.org/Proteins/SECSG/1z2u TOPSAN]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/UBC2_CAEEL UBC2_CAEEL]] Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 25: | Line 27: | ||
[[Category: Caenorhabditis elegans]] | [[Category: Caenorhabditis elegans]] | ||
[[Category: Ubiquitin--protein ligase]] | [[Category: Ubiquitin--protein ligase]] | ||
| - | [[Category: DiGiamamarino, E | + | [[Category: DiGiamamarino, E]] |
| - | [[Category: Gavira, J A | + | [[Category: Gavira, J A]] |
| - | [[Category: Liu, Z J | + | [[Category: Liu, Z J]] |
| - | [[Category: Meehan, E | + | [[Category: Meehan, E]] |
| - | [[Category: Ng, J D | + | [[Category: Ng, J D]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Tempel, W | + | [[Category: Tempel, W]] |
| - | [[Category: Wang, B C | + | [[Category: Wang, B C]] |
[[Category: Caenorhabditis elegan]] | [[Category: Caenorhabditis elegan]] | ||
[[Category: Ligase]] | [[Category: Ligase]] | ||
| - | [[Category: Protein structure initiative]] | + | [[Category: PSI, Protein structure initiative]] |
[[Category: Proteosome pathway]] | [[Category: Proteosome pathway]] | ||
| - | [[Category: Psi]] | ||
[[Category: Secsg]] | [[Category: Secsg]] | ||
| - | [[Category: Southeast collaboratory for structural genomic]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: Ubiquitin-conjugating enzyme]] | [[Category: Ubiquitin-conjugating enzyme]] | ||
Revision as of 09:32, 25 December 2014
The 1.1A crystallographic structure of ubiquitin-conjugating enzyme (ubc-2) from Caenorhabditis elegans: functional and evolutionary significance
| |||||||||||
Categories: Caenorhabditis elegans | Ubiquitin--protein ligase | DiGiamamarino, E | Gavira, J A | Liu, Z J | Meehan, E | Ng, J D | Structural genomic | Tempel, W | Wang, B C | Caenorhabditis elegan | Ligase | PSI, Protein structure initiative | Proteosome pathway | Secsg | Ubiquitin-conjugating enzyme
