1z2u
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1z2u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z2U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z2U FirstGlance]. <br> | <table><tr><td colspan='2'>[[1z2u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z2U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z2U FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BU3:(R,R)-2,3-BUTANEDIOL'>BU3</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BU3:(R,R)-2,3-BUTANEDIOL'>BU3</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ubc-2, let-70 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 Caenorhabditis elegans])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ubc-2, let-70 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 Caenorhabditis elegans])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ubiquitin--protein_ligase Ubiquitin--protein ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.19 6.3.2.19] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ubiquitin--protein_ligase Ubiquitin--protein ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.19 6.3.2.19] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z2u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z2u RCSB], [http://www.ebi.ac.uk/pdbsum/1z2u PDBsum], [http://www.topsan.org/Proteins/SECSG/1z2u TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z2u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z2u RCSB], [http://www.ebi.ac.uk/pdbsum/1z2u PDBsum], [http://www.topsan.org/Proteins/SECSG/1z2u TOPSAN]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/UBC2_CAEEL UBC2_CAEEL]] Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Caenorhabditis elegans]] | [[Category: Caenorhabditis elegans]] | ||
[[Category: Ubiquitin--protein ligase]] | [[Category: Ubiquitin--protein ligase]] | ||
| - | [[Category: DiGiamamarino, E | + | [[Category: DiGiamamarino, E]] |
| - | [[Category: Gavira, J A | + | [[Category: Gavira, J A]] |
| - | [[Category: Liu, Z J | + | [[Category: Liu, Z J]] |
| - | [[Category: Meehan, E | + | [[Category: Meehan, E]] |
| - | [[Category: Ng, J D | + | [[Category: Ng, J D]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Tempel, W | + | [[Category: Tempel, W]] |
| - | [[Category: Wang, B C | + | [[Category: Wang, B C]] |
[[Category: Caenorhabditis elegan]] | [[Category: Caenorhabditis elegan]] | ||
[[Category: Ligase]] | [[Category: Ligase]] | ||
| - | [[Category: Protein structure initiative]] | + | [[Category: PSI, Protein structure initiative]] |
[[Category: Proteosome pathway]] | [[Category: Proteosome pathway]] | ||
| - | [[Category: Psi]] | ||
[[Category: Secsg]] | [[Category: Secsg]] | ||
| - | [[Category: Southeast collaboratory for structural genomic]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: Ubiquitin-conjugating enzyme]] | [[Category: Ubiquitin-conjugating enzyme]] | ||
Revision as of 09:32, 25 December 2014
The 1.1A crystallographic structure of ubiquitin-conjugating enzyme (ubc-2) from Caenorhabditis elegans: functional and evolutionary significance
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Categories: Caenorhabditis elegans | Ubiquitin--protein ligase | DiGiamamarino, E | Gavira, J A | Liu, Z J | Meehan, E | Ng, J D | Structural genomic | Tempel, W | Wang, B C | Caenorhabditis elegan | Ligase | PSI, Protein structure initiative | Proteosome pathway | Secsg | Ubiquitin-conjugating enzyme
