2d93
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2d93]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D93 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D93 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2d93]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D93 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D93 FirstGlance]. <br> | ||
- | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KAZUSA cDNA ha02566 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KAZUSA cDNA ha02566 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
- | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d93 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2d93 RCSB], [http://www.ebi.ac.uk/pdbsum/2d93 PDBsum], [http://www.topsan.org/Proteins/RSGI/2d93 TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d93 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2d93 RCSB], [http://www.ebi.ac.uk/pdbsum/2d93 PDBsum], [http://www.topsan.org/Proteins/RSGI/2d93 TOPSAN]</span></td></tr> |
- | <table> | + | </table> |
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/RPGF6_HUMAN RPGF6_HUMAN]] Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP.<ref>PMID:12581858</ref> <ref>PMID:11524421</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
+ | == References == | ||
+ | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Hayashi, F | + | [[Category: Hayashi, F]] |
- | [[Category: Inoue, K | + | [[Category: Inoue, K]] |
- | [[Category: Muto, Y | + | [[Category: Muto, Y]] |
- | [[Category: | + | [[Category: Structural genomic]] |
- | [[Category: Yokoyama, S | + | [[Category: Yokoyama, S]] |
[[Category: Cnmp_binding domain]] | [[Category: Cnmp_binding domain]] | ||
[[Category: National project on protein structural and functional analyse]] | [[Category: National project on protein structural and functional analyse]] | ||
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[[Category: Rap guanine nucleotide exchange factor 6]] | [[Category: Rap guanine nucleotide exchange factor 6]] | ||
[[Category: Rapgef6]] | [[Category: Rapgef6]] | ||
- | [[Category: Riken structural genomics/proteomics initiative]] | ||
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
- | [[Category: Structural genomic]] |
Revision as of 10:06, 25 December 2014
Solution structure of the cNMP_binding domain of human Rap guanine nucleotide exchange factor 6
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Categories: Homo sapiens | Hayashi, F | Inoue, K | Muto, Y | Structural genomic | Yokoyama, S | Cnmp binding domain | National project on protein structural and functional analyse | Nppsfa | Pdz domain containing guanine nucleotide exchange factor 2 | Pdz-gef2 | Ra-gef-2 | Rap guanine nucleotide exchange factor 6 | Rapgef6 | Rsgi | Signaling protein