4uqq
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uqq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uqq RCSB], [http://www.ebi.ac.uk/pdbsum/4uqq PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uqq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uqq RCSB], [http://www.ebi.ac.uk/pdbsum/4uqq PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GRIK2_RAT GRIK2_RAT]] Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus. Modulates cell surface expression of NETO2 (By similarity).<ref>PMID:17486098</ref> <ref>PMID:17115050</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Bartesaghi, A | + | [[Category: Bartesaghi, A]] |
| - | [[Category: Chittori, S | + | [[Category: Chittori, S]] |
| - | [[Category: Kumar, J | + | [[Category: Kumar, J]] |
| - | [[Category: Mayer, M L | + | [[Category: Mayer, M L]] |
| - | [[Category: Meyerson, J R | + | [[Category: Meyerson, J R]] |
| - | [[Category: Pierson, J | + | [[Category: Pierson, J]] |
| - | [[Category: Rao, P | + | [[Category: Rao, P]] |
| - | [[Category: Subramaniam, S | + | [[Category: Subramaniam, S]] |
[[Category: Ion channel]] | [[Category: Ion channel]] | ||
[[Category: Membrane protein]] | [[Category: Membrane protein]] | ||
[[Category: Transport protein]] | [[Category: Transport protein]] | ||
Revision as of 10:07, 25 December 2014
Electron density map of GluK2 desensitized state in complex with 2S,4R-4-methylglutamate
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