1tej
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1tej]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Echis_carinatus Echis carinatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TEJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TEJ FirstGlance]. <br> | <table><tr><td colspan='2'>[[1tej]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Echis_carinatus Echis carinatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TEJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TEJ FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tej FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tej OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1tej RCSB], [http://www.ebi.ac.uk/pdbsum/1tej PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tej FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tej OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1tej RCSB], [http://www.ebi.ac.uk/pdbsum/1tej PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DISS_ECHCA DISS_ECHCA]] May bind to both alpha-IIb/beta-3 (ITGA2B/ITGB3) and alpha-V/beta-3 (ITGAV/ITGB3) integrins, and may inhibit platelet aggregation. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Echis carinatus]] | [[Category: Echis carinatus]] | ||
| - | [[Category: Betzel, C | + | [[Category: Betzel, C]] |
| - | [[Category: Bilgrami, S | + | [[Category: Bilgrami, S]] |
| - | [[Category: Kaur, P | + | [[Category: Kaur, P]] |
| - | [[Category: Perbandt, M | + | [[Category: Perbandt, M]] |
| - | [[Category: Singh, T P | + | [[Category: Singh, T P]] |
| - | [[Category: Yadav, S | + | [[Category: Yadav, S]] |
[[Category: Cryatal structure]] | [[Category: Cryatal structure]] | ||
[[Category: Disintegrin]] | [[Category: Disintegrin]] | ||
[[Category: Heterodimer]] | [[Category: Heterodimer]] | ||
[[Category: Protein binding]] | [[Category: Protein binding]] | ||
Revision as of 10:13, 25 December 2014
Crystal structure of a disintegrin heterodimer at 1.9 A resolution.
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