3bpu

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3bpu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BPU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BPU FirstGlance]. <br>
<table><tr><td colspan='2'>[[3bpu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BPU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BPU FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAGI1, BAIAP1, BAP1, TNRC19 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAGI1, BAIAP1, BAP1, TNRC19 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bpu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bpu RCSB], [http://www.ebi.ac.uk/pdbsum/3bpu PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bpu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bpu RCSB], [http://www.ebi.ac.uk/pdbsum/3bpu PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MAGI1_HUMAN MAGI1_HUMAN]] May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Arrowsmith, C H]]
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[[Category: Cooper, C.]]
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[[Category: Cooper, C]]
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[[Category: Delft, F von.]]
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[[Category: Delft, F von]]
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[[Category: Doyle, D A.]]
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[[Category: Doyle, D A]]
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[[Category: Edwards, A M.]]
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[[Category: Edwards, A M]]
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[[Category: Elkins, J.]]
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[[Category: Elkins, J]]
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[[Category: Hozjan, V.]]
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[[Category: Hozjan, V]]
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[[Category: Oppermann, U.]]
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[[Category: Oppermann, U]]
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[[Category: Pike, A C.W.]]
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[[Category: Pike, A C.W]]
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[[Category: Pilka, E S.]]
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[[Category: Pilka, E S]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Structural genomic]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt, J]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Cell junction]]
[[Category: Cell junction]]
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[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Sgc]]
[[Category: Sgc]]
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[[Category: Structural genomics consortium]]
 
[[Category: Tight junction]]
[[Category: Tight junction]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 10:15, 25 December 2014

Crystal structure of the 3rd PDZ domain of human membrane associated guanylate kinase, C677S and C709S double mutant

3bpu, resolution 1.60Å

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