1prq
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1prq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Acanthamoeba_castellanii Acanthamoeba castellanii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PRQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PRQ FirstGlance]. <br> | <table><tr><td colspan='2'>[[1prq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Acanthamoeba_castellanii Acanthamoeba castellanii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PRQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PRQ FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1prq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1prq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1prq RCSB], [http://www.ebi.ac.uk/pdbsum/1prq PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1prq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1prq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1prq RCSB], [http://www.ebi.ac.uk/pdbsum/1prq PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PRO1A_ACACA PRO1A_ACACA]] Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Acanthamoeba castellanii]] | [[Category: Acanthamoeba castellanii]] | ||
| - | [[Category: Almo, S C | + | [[Category: Almo, S C]] |
| - | [[Category: Fedorov, A A | + | [[Category: Fedorov, A A]] |
| - | [[Category: Lattman, E E | + | [[Category: Lattman, E E]] |
| - | [[Category: Pollard, T D | + | [[Category: Pollard, T D]] |
| - | [[Category: Way, M | + | [[Category: Way, M]] |
[[Category: Actin-binding protein]] | [[Category: Actin-binding protein]] | ||
[[Category: Contractile protein]] | [[Category: Contractile protein]] | ||
Revision as of 10:16, 25 December 2014
ACANTHAMOEBA CASTELLANII PROFILIN IA
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