4r9l

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4r9l]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R9L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R9L FirstGlance]. <br>
<table><tr><td colspan='2'>[[4r9l]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R9L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R9L FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HYH:(2R)-2-HYDROXYHEXANAMIDE'>HYH</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HYH:(2R)-2-HYDROXYHEXANAMIDE'>HYH</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1nww|1nww]], [[1nu3|1nu3]], [[4r9k|4r9k]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1nww|1nww]], [[1nu3|1nu3]], [[4r9k|4r9k]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Limonene-1,2-epoxide_hydrolase Limonene-1,2-epoxide hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.3.2.8 3.3.2.8] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Limonene-1,2-epoxide_hydrolase Limonene-1,2-epoxide hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.3.2.8 3.3.2.8] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r9l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r9l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4r9l RCSB], [http://www.ebi.ac.uk/pdbsum/4r9l PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r9l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r9l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4r9l RCSB], [http://www.ebi.ac.uk/pdbsum/4r9l PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/LIMA_RHOER LIMA_RHOER]] Catalyzes the conversion of limonene-1,2-epoxide to limonene-1,2-diol. Can use both the (-) and (+) isomers of limonene-1,2-epoxide as substrates and also has some activity with 1-methylcyclohexene oxide, cyclohexene oxide and indene oxide as substrates.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Limonene-1,2-epoxide hydrolase]]
[[Category: Limonene-1,2-epoxide hydrolase]]
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[[Category: Dijkstra, B W.]]
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[[Category: Dijkstra, B W]]
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[[Category: Floor, R J.]]
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[[Category: Floor, R J]]
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[[Category: Janssen, D B.]]
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[[Category: Janssen, D B]]
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[[Category: Jekel, P A.]]
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[[Category: Jekel, P A]]
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[[Category: Scheltinga, A C.Terwisscha van.]]
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[[Category: Scheltinga, A C.Terwisscha van]]
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[[Category: Wijma, H J.]]
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[[Category: Wijma, H J]]
[[Category: Engineered]]
[[Category: Engineered]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]

Revision as of 10:17, 25 December 2014

Structure of a thermostable elevenfold mutant of limonene epoxide hydrolase from Rhodococcus erythropolis, containing two stabilizing disulfide bonds

4r9l, resolution 1.80Å

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