2gpw

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2gpw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GPW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GPW FirstGlance]. <br>
<table><tr><td colspan='2'>[[2gpw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GPW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GPW FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1w93|1w93]], [[1w96|1w96]], [[1dv1|1dv1]], [[1dv2|1dv2]], [[1bnc|1bnc]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1w93|1w93]], [[1w96|1w96]], [[1dv1|1dv1]], [[1dv2|1dv2]], [[1bnc|1bnc]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">accC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">accC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Biotin_carboxylase Biotin carboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.14 6.3.4.14] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Biotin_carboxylase Biotin carboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.14 6.3.4.14] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gpw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gpw RCSB], [http://www.ebi.ac.uk/pdbsum/2gpw PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gpw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gpw RCSB], [http://www.ebi.ac.uk/pdbsum/2gpw PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ACCC_ECOLI ACCC_ECOLI]] This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Biotin carboxylase]]
[[Category: Biotin carboxylase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Chang, G G.]]
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[[Category: Chang, G G]]
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[[Category: Chou, C Y.]]
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[[Category: Chou, C Y]]
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[[Category: Shen, Y.]]
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[[Category: Shen, Y]]
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[[Category: Tong, L.]]
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[[Category: Tong, L]]
[[Category: Atp-grasp]]
[[Category: Atp-grasp]]
[[Category: Biotin-dependent]]
[[Category: Biotin-dependent]]

Revision as of 10:26, 25 December 2014

Crystal Structure of the Biotin Carboxylase Subunit, F363A Mutant, of Acetyl-CoA Carboxylase from Escherichia coli.

2gpw, resolution 2.20Å

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