1zp2

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1zp2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZP2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZP2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1zp2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZP2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZP2 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">srb11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4896 Schizosaccharomyces pombe])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">srb11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4896 Schizosaccharomyces pombe])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zp2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zp2 RCSB], [http://www.ebi.ac.uk/pdbsum/1zp2 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zp2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zp2 RCSB], [http://www.ebi.ac.uk/pdbsum/1zp2 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/SRB11_SCHPO SRB11_SCHPO]] Component of the Cdk8 module/Srb8-11 module which is a regulatory module of the Mediator complex that regulates basal RNA polymerase II transcription. The Cdk8 module may sterically hinder the interaction between Mediator and RNA polymerase II leading to transcriptional repression of a subset of genes regulated by Mediator.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Schizosaccharomyces pombe]]
[[Category: Schizosaccharomyces pombe]]
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[[Category: Baumli, S.]]
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[[Category: Baumli, S]]
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[[Category: Cramer, P.]]
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[[Category: Cramer, P]]
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[[Category: Hoeppner, S.]]
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[[Category: Hoeppner, S]]
[[Category: Cyclin repeat domain]]
[[Category: Cyclin repeat domain]]
[[Category: Transcription-cell cycle complex]]
[[Category: Transcription-cell cycle complex]]

Revision as of 10:35, 25 December 2014

Structure of the Mediator subunit cyclin C

1zp2, resolution 3.00Å

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